Kenya AIDS Vaccine Initiative (KAVI) was established in 1998 as a research unit within the
Department of Medical Microbiology, College of Health Sciences, University of Nairobi, with
an initial mission to conduct basic research in epidemiology of HIV and to carryout HIV/AIDs
Over the years, KAVI experienced tremendous growth as a result of sustained funding, hence
the development of human capacity, infrastructure and community mobilization catchment
areas. By 2013, KAVI as a research unit had successfully undertaken eight HIV vaccine trials,
two drug trials, thirteen epidemiological and basic research projects in addition to pioneering
the development of mucosal sampling and standardization of mucosal immune assays. KAVI
has also greatly assisted in the development of human capacity within the East African region
by training various Institutional Ethics boards and clinical research personnel on research
ethics, Good Clinical Practice (GCP) and Good Clinical and Laboratory Practice (GCLP). KAVI
has also been involved in the strengthening of Laboratory management systems of various
health institutions to prepare the institutions for accreditation.
The KAVI Institute of Clinical Research (KAVI-ICR) is a word-class research hub at the College of Health Sciences, University of Nairobi, spearheading research and training in global health. KAVI Institute of Clinical Research has conducted basic HIV, epidemiology research and eight HIV vaccine trials, ten basic science, and epidemiological research studies. KAVI Institute of Clinical Research programs are geared to understanding the underlying determinants of good health for prevention of both communicable and non-communicable diseases are urgently needed. Linking various health determinants to establish the best interventions and preventive measures is a key outcome from global health research.
KAVI Institute of Clinical Research focuses on four themes coupled with attractive career paths that are attracting the best talent in Africa and serve the best interests of the general population. The Non-Communicable Diseases track includes Cancers-such as breast, colon, prostate cancers as well as the diseases of the cardiovascular, respiratory, and endocrine systems. The Communicable Disease track focuses on HIV/AIDS, along with research on tuberculosis, zoonoses, and childhood respiratory and gastrointestinal diseases. T he Clinical Trials track runs HIV vaccine trials in addition to trials for other products including chemotherapy drug trials. Finally, the Knowledge Translation track brings research, policy, and implementation together by building relationships and opportunities for collaboration between researchers and those who benefit from and use the research results.